Syntheses and Ring Closure Reactions of 1-Aryl-4-acylsemicarbazides
نویسندگان
چکیده
منابع مشابه
SYNTHESES, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF 2-ARYL-4- QUINOLINE- CARBOXAMIDE DERIVATIVES
Reaction of aryl methyl ketone with isatin in the presence of a base afforded 2- arylquinoline-4-carboxylic acid (3). Reaction of diazomethane with compound 3 yielded the ester 4. Compound 5 was prepared from the reaction of N, N'-dialkylethyl (or propyl) arnine with 4. Addition of hydrazine hydrate to compound 4a gave 2- (2- pyridyl) quinoline-4-carboxylic acid hydrazide (6). Reaction of l...
متن کاملThe acid-mediated ring opening reactions of α-aryl-lactams.
4-Aryl-azetidin-2-ones (β-lactams) undergo ring opening with triflic acid to give cinnamamides which, in benzene, react further to give 3-aryl-3-phenyl-propionamides. Prolonged reaction times in benzene give 3,3-diphenyl-propionamide via an aryl/phenyl exchange. Lactams of ring size 7 and higher also ring open, but only 7- and 8-membered rings give pure diphenylalkylamides. AlCl(3) only ring op...
متن کاملRing-opening reactions of 2-aryl-3,4-dihydropyrans with nucleophiles.
Ring-opening reactions of 2-aryl-3,4-dihydropyrans with nucleophiles were reported for the first time. A possible mechanism was also proposed. Finally, this method was used in the synthesis of a novel tetrahydrocarbazole derivative that possesses a biologically active skeleton.
متن کاملsyntheses, antibacterial and antifungal activities of 2-aryl-4- quinoline- carboxamide derivatives
reaction of aryl methyl ketone with isatin in the presence of a base afforded 2- arylquinoline-4-carboxylic acid (3). reaction of diazomethane with compound 3 yielded the ester 4. compound 5 was prepared from the reaction of n, n'-dialkylethyl (or propyl) arnine with 4. addition of hydrazine hydrate to compound 4a gave 2- (2- pyridyl) quinoline-4-carboxylic acid hydrazide (6). reaction of ...
متن کاملUnexpected hydroxylamine-induced ring-closure reactions of meso-tetraphenylsecochlorin bisaldehyde.
Reaction of meso-tetraphenylsecochlorin bisaldehyde with hydroxylamine results in the formation of the known meso-tetraphenyl-2-nitroporphyrin and the novel meso-tetraphenylimidazolophorphyrin. The products are the result of two diverging pathways of the presumed intermediate monooxime monoaldehyde that are unusual and surprising, but fully rationalized. The structures of both products were con...
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ژورنال
عنوان ژورنال: Nippon kagaku zassi
سال: 1968
ISSN: 0369-5387,2185-0917
DOI: 10.1246/nikkashi1948.89.69